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Neocutis – Milwaukee, WI

High Protein Skin Care

neocutis_logoPhysicians have known for many years that fetal skin has a unique ability to heal wounds without scarring. Inspired by this knowledge, medical researchers at the University Hospital of Lausanne, in Switzerland, created a biotechnology process to extract the rich proteins responsible for scarless wound healing from cultured fetal skin cells. Using this fetal skin, a dedicated cell bank was established for developing new skin treatments. Originally the cell extract was used to promote wound healing for burn treatments. Today this same cell bank has been expanded to provide a lasting supply of cells for producing the proprietary skin care ingredients in NEOCUTIS.

Processed Skin Cell Proteins

NEOCUTIS proprietary technology uses cultured skin cells to obtain an optimal, naturally balanced mixture of fetal skin nutrients including cytokines, growth factors and antioxidants. This mixture is called PSP®, which stands for “Processed Skin Cell Proteins”, and it is derived following stringent biotechnology procedures. PSP® provides the most complete and balanced combination of human growth factors and cytokines currently available.

Skin Cell Protein Donation

Since the 1930s, the international medical community has used donated fetal tissue to better understand cell biology and as an essential tool in the development of vaccines, which are credited with saving millions of lives worldwide. The 1954 Nobel Prize for medicine was awarded to researchers who utilized fetal kidney cells to develop the polio vaccine. The view at NEOCUTIS – shared by most medical professionals and patients – is that the limited, prudent and responsible use of donated fetal skin tissue can be used for significant medical benefit to ease suffering, speed healing, save lives, and improve the well-being of many patients around the globe.

The small skin donation that, ultimately, made the development of NEOCUTIS possible originated from a single terminated pregnancy that could not survive to term and was deemed medically necessary by the attending physicians. This voluntary donation to medical research was granted by the parents with their written consent, and was performed in adherence with strict Swiss laws that regulate organ and tissue donations.

NEOCUTIS products do not directly use the originally donated tissue in any way. All the cultured skin cells (grown from a dedicated cell bank) used to produce PSP® have been grown from the initial fetal tissue acquired in 2004. These are not embryonic stem cells. No additional fetal biopsies will ever be required. The cell bank is stored frozen in liquid nitrogen and can be kept for many years, thereby providing a sustained supply of cells for PSP® production over decades. In fact, this cell bank enables the production of some 900 million biological bandages for patients suffering from severe wounds, burns, and other serious skin conditions.

Our Skin is in Permanent Need of Bio-restoration

Our skin is the largest and organs of our body. It establishes, controls, and transmits contacts with the external world. Beyond the classical image of the skin as a barrier organ and providing physical resistance to mechanical stress, it operates as a huge and highly active bio-factory in the synthesis, processing, and metabolism of skin constituents including structural proteins, polysaccharides, lipids and a diversity of signaling molecules. PSP® plays a vital role in not only helping to maintain proper skin function, but to promote skin function at a younger, more rejuvenated level.

Listed below are some of the specialty products NEOCUTIS offers, and that we really like.


JOURNEE Bio-restorative Day Cream with PSP® SPF 30+

Neocutis-Journee-Day-Cream-with-PSPThe most complete anti-aging day cream with PSP®, anti-oxidants, hyaluronic acid and UVA/UVB spf 30+ to protect, hydrate, and help improve the look of aged skin. JOURNEE simultaneously addresses the visible signs of both chronological and premature skin aging.

  • Formulated with PSP® 0.05%
  • Helps smooth the appearance of fine lines and wrinkles.
  • Provides long lasting hydration for radiant, luminous skin.
  • Potent anti-oxidant blend of polyphenol rich green tea extract and stabilized vitamins C and E act synergistically to help fight against daily environmental assaults.
  • Hyaluronic acid for moisture retention
  • Fast absorbing, skin-toned, non-greasy formulation blends flawlessly into skin.
  • Ideal for all skin types.
  • Apply in AM


NEOCUTIS BIO-CREAM Bio-restorative Skin Cream with PSP®

Neocutis-Biorestorative-Cream-with -PSPThe first and original skin cream formulated with PSP®, the most complete protein blend of Human Growth Factors, Cytokines and Interleukins available to help improve appearance of aged skin and soothe skin. Clinically proven to reduce the appearance of facial wrinkles after two months of daily use*.

  • Formulated with PSP® 0.05%
  • Helps reduce the appearance of fine lines and wrinkles.
  • Improves skin texture and tone for renewed radiance.
  • Enhances skin firmness.
  • Helps promote recovery and skin restoration after cosmetic or dermatological procedures such as chemical peels, micro-dermabrasion, laser and/or light treatments, and cosmetic surgical
  • Ideal for normal to dry skin types.
  • Apply in AM and/or PM

*Read more about NEOCUTIS Bio-Cream with PSP®


NEOCUTIS BIO-GEL Bio-restorative Hydrogel with PSP®

Unique Hydrogel combines PSP® and Hydrating Hyaluronic Acid to help restore radiance to aged skin. Formulated with PSP®, a complete protein blend of Human Growth Factors, Cytokines and Interleukins to help improve signs of aged skin and soothe skin.

  • Formulated with PSP® 0.05%
  • Helps reduce the appearance of fine lines and wrinkles.
  • Improves skin texture and tone to restore luminosity.
  • Enhances skin firmness.
  • Oil-free hydrogel texture is ideal for men.
  • Nurtures, nourishes and refreshed stressed looking skin after non-invasive cosmetic procedures such as fillers, micro-dermabrasion and light peels.
  • Helps soothe skin when used in combination with topical medications such as rosacea treatments, or retinoids.
  • Ideal for normal to oily skin types.
  • Apply in AM and/or PM


LUMIERE Bio-restorative Eye Cream with PSP®

Lumiere-Biorestorative-Eye-Cream-with-PSPIntensive line smoothing eye cream with PSP® helps improve the signs of aging. Formulated with 30% more PSP® and hyaluronic acid to help firm and hydrate the delicate skin under and around the eyes.

  • Formulated with PSP® 0.065%
  • Helps reduce the appearance of under eye darkness.
  • Smoothes the appearance of fine lines and wrinkles.
  • Caffeine helps alleviate signs of skin puffiness.
  • Soothes and refreshes the delicate eye area to help minimize signs of fatigue.
  • Ideal for all skin types.
  • Apply in AM and/or PM

Recently, a large clinical study with LUMIERE Bio-restorative Eye Cream was completed. The study demonstrated that LUMIERE helps to significantly reduce the signs of aged and stressed skin around the eye after six weeks of twice daily use.


BIO-SREUM Bio-restorative Serum with PSP

Neocutis-Biorestorative-Serum-with-PSPThe most intensive stimulating PSP® serum available with an unprecedented concentration of PSP® (100%more) to help reduce the signs of skin aging in as little as 7 days.* Clinically effective PSP® combined with Amino Acids and a Bio-mimetic Peptide to help safeguard against environmental damage. Skin plumping hyaluronic acid and line softening technology work synergistically to help visibly transform the appearance of skin

  • Formulated with PSP® 0.1%
  • Skin looks plump with increased hydration.
  • Fine lines and wrinkles appear to be virtually erased and softened.
  • Improves skin tone and texture; Skin feels tighter.
  • Ideal for all skin types.
  • Apply in AM and/or PM
  • Also available as an Intensive Spot Treatment in a portable pen applicator for stubborn lines and wrinkles.


NEOCUTIS RéACTIVE Anti-oxidant Serum

Neocutis-Reactive-Antioxidant-Serum-powered-by-Vitaplex-CRéACTIVE helps preserve your skin’s youthful look with an advanced anti-oxidant shield. VITAPLEX C™ offers one of the most complete anti-oxidant defense systems through a unique blend of 15% Vitamin C, other potent anti-oxidants and an energizing amino acid.

Powered by VITAPLEX C™  Benefits:

  • Free radical neutralization
  • Anti-oxidant regeneration
  • Provides 250 times more Vitamin C than an orange
  • Helps slow down the appearance of skin aging due to oxidative stress
  • Minimizes the look of  redness caused by oxidative stress
  • Helps even out skin tone

Use AM and/or PM as the last step of your skin care regimen to provide a first line of defense.   1fl oz. / 30ml

RéACTIVE anti-oxidant serum offers more powerful antioxidant protection than other serums. The left side of the apple was protected with RéACTIVE, while the right side was treated with another popular brand. Elapsed time photos show oxidative changes at 12hr and 36hr.



HYALIS Refining Serum

Neocutis-Hyalis-Hydrating-Serum-Powered-by-HyaluronateFast Acting Hydrating serum helps deliver immediate moisture for youthful, radiant looking skin. Formulated with the highest concentration of pharmaceutical grade 1% Sodium Hyaluronate (Hyaluronic Acid) for maximum purity and efficacy

  • Helps smooth and plump skin to help minimize the signs of skin aging.
  • Intensive hydrating action leaves skin supple and smooth.
  • Helps to soothe and hydrate stressed, irritated skin.
  • Great to use as an adjunct for drying dermatological treatments in rosacea, anti-acne and retinoid regimens.
  • Ideal for all skin types.
  • Incorporate into any skin care regimen.
  • Apply in AM and/or PM


BLANCHE Skin Lightening Cream with MELAPLEX® (Hydroquinone USP, 4%)

Neocutis-Blanche-Skin-Lightening-Cream-with-4%-hydroquinone-Powered-by-MelaplexThe formation of skin pigment, called melanin, is complex with multiple pathways. Sun exposure is the primary cause of dyspigmentation/hyper-pigmentation. BLANCHE Skin Lightening Cream uses a combination of 4% Hydroquinone and MELAPLEX® to disrupt skin pigment formation.

Hydroquinone* has long been considered the standard in dermatology for treating skin discoloration. Hydroquinone functions as a tyrosinase inhibitor, blocking one enzymatic step in the formation of melanin pigment.

MELAPLEX® offers a hydroquinone-free alternative for long-term use in the management of skin discoloration. MELAPLEX® is a proprietary skin brightening complex consisting of four ingredients to address skin color from a new perspective. MELAPLEX® helps minimize tyrosinase activity with Phenylethyl Resorcinol—but also contains other ingredients including Leucine, a competitive precursor of melanin formation, Undecylenoyl Phenylalanine to help minimize sun induced melanin formation and Sodium Glycerophosphate, aiming to target several steps of melanin formation including the transfer of the melanosome into keratinocytes. By addressing pigment formation at multiple steps, MELAPLEX® helps reduce the appearance of skin discolorations and visibly brightens skin tone.


*Hydroquinone may not be suitable for long-term use.


PERLE Skin Brightening Cream formulated with MELAPLEX®

Neocutis-Perle-Skin-Brightening-Cream-Powered-by-MelaplexIlluminate skin with a hydroquinone-free alternative to improve the appearance of skin discolorations and uneven skin tone.

MELAPLEX®, an exclusive skin brightening complex, contains four ingredients designed to target four different pathways in the formation of skin pigment. By addressing pigment formation at multiple steps, MELAPLEX® helps reduce the appearance of skin discolorations and visibly brightens skin tone without the need of hydroquinone.

  • Visibly diminish the appearance of dark spots and uneven skin tone.
  • Restore the look of skin clarity and tone for a more luminous, younger looking complexion.
  • Replenish skin’s texture with Shea Butter, Jojoba Oil and anti-oxidants C and E.
  • MELAPLEX® offers a hydroquinone-free alternative for long-term use in the management of the signs of skin discoloration.
  • Suitable for all skin types.
  • Apply in AM and/or PM