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Kybella – Milwaukee, WI

Injection Treatment for the Double Chin

Do you suffer from unsightly fullness under your chin? Does this excess fat remain, despite diet and exercise, and make you look older and heavier than you actually are? If so, you are not alone – many people are bothered by excess fat under their chin. But now, for the first time, there is an FDA-approved {nonsurgical} injectable treatment that improves the contour and reduces the fullness under your chin.


Submental Fullness is Unsightly

Submental fullness, commonly referred to as the “double chin”, affects a large number of men and women. This excess subcutaneous fat can be familial, caused by aging, or the result of weight gain, and can vary widely in severity. In any of these cases, the dreaded double chin tends to be unattractive, making us look older and heavier than we would otherwise like.

Historical Management of Submental Fullness

The treatments available to manage areas of excess fat have historically been quite limited. Injectable treatments to reduce subcutaneous fat are not new.  These injectable treatments, referred to as lipodissolve or mesotherapy, have used substances like deoxycholic acid to break fat cells apart without surgery. Utilizing multiple treatment sessions, these injectables were marketed to serve as an alternative to surgical liposuction procedures. Inconsistencies have existed in the composition and concentration of the injectable substances, as well as the injection techniques – so there have been no well-controlled clinical studies to show the efficacy, safety, or reproducibility of the lipodissolve results. In recent years there have been other advances made in the nonsurgical approach to treating unwanted fat. High intensity ultrasound waves and significant cooling have both successfully demonstrated results in larger body areas, but these treatments have not been applicable to the neck and chin. The most common treatment for excess fat under the chin has been liposuction. Aspiration of submental fat has been safely performed as a primary operation, or in combination with a facelift and neck lift.

Introducing Kybella®

But now, submental fullness can be safely treated with an injectable approach. Kybella (deoxycholic acid) is the first and only FDA-approved injectable drug that contours and improves the appearance of moderate to severe submental fullness in adults. Kybella was approved for use on April 29, 2015 and will be available to patients in August 2015.

What Makes the Kybella® Treatment Different?

A Kybella treatment lacks the inconsistencies that existed in previous injection approaches to fat lysis. The deoxycholic acid in Kybella is a natural, non-animal based compound manufactured under strict control by Hospira here in the United States. Packaged at a specific standardized concentration per vial, a Kybella treatment offers a consistent and uniform injection process that produces safe and predictable results.

How Does Kybella® Work?

The active ingredient in Kybella is deoxycholic acid. This is a naturally occurring molecule in the human body that aids in the breakdown and absorption of dietary fats. Deoxycholic acid is a lipophilic (lipid/fat loving) molecule that can easily insert itself into fats and lipids, breaking them apart. When injected into the fat beneath the chin, Kybella causes the destruction of fat cells by inserting itself into the cell membrane (lipid bilayer). The deoxycholic acid essentially punches holes in the fat cell membrane, causing it to burst. Once the fat cell is destroyed, it is cleared by normal metabolic processes and cannot store or re-accumulate fat.


Individual results may vary. *

Who is a Candidate for Kybella®?

Kybella is not appropriate for all individuals who have fullness under their chin. Adult patients with moderate-to-severe fat below the chin should be good candidates for Kybella patients with prominent platysmal bands or significant loose skin may not achieve ideal results. Using Kybella to treat fat outside of the submental region is not approved, and is not recommended.


Individual results may vary. *

The Kybella® Treatment

Chin contouring with Kybella requires a series of treatment sessions. These injection sessions are typically performed about four weeks apart. Each Kybella session is individualized, based upon the amount of submental fat that is present. A series of injections are placed into the fat under the chin; a patient may receive up to 50 injections in a single treatment session depending upon the amount of fat present. A typical in-office treatment usually takes 20-30 minutes or so. The average patient requires two to four injection sessions.

FDA Clinical Trial for Kybella® Approval

The Kybella treatment has been well studied and documented. There are more than 20 Kybella studies worldwide, involving more than 2600 patients. In the pivotal clinical study for FDA approval, 1022 patients with moderate to severe submental fullness were evaluated. A five-point evaluation scale was used to categorize the amount of subcutaneous fat under the chin – absent, mild, moderate, severe, and extreme. The goal of the study was to demonstrate a one- or two-grade improvement in the appearance of submental fullness. In other words, the Kybella treatment was deemed to be successful if a person with “severe” fullness improved to the moderate or mild category; or, if a patient with “moderate” fullness improved to the mild or absent category. Both the patients and the doctors rated the results separately. And post-treatment ratings were performed without looking at the photographs taken before the study began. Both the patient and the doctor had to agree that there was at least a one-grade improvement in the appearance of submental fullness in order for the treatment to be classified as a success. 68% of treated patients met this one-grade improvement. There was a 79% overall satisfaction rating with the Kybella treatment. The majority of patients saw improvement in the contouring of their chin profile in 2 to 4 treatments; however some patients required up to six treatments to achieve results. After being treated with Kybella, patients reported improvement in self-perception, based on their chin profile.

Common Side Effects and Adverse Reactions

The most common side effects following Kybella treatment include swelling, bruising, pain, redness, numbness and/or areas or hardness in the treatment area. In clinical trials, the occurrence and severity of the side effects decreased with subsequent Kybella treatments. Kybella can cause more serious side effects such as nerve injury.

If you are bothered by fullness under your chin and want to learn more about Kybella please call our office to schedule a consultation >> 414-443-0033 .